Rick discovers a possible safe haven. Shane must go on a dangerous mission to get needed medical supplies.

Dark secrets are revealed as Coulson and his team put everything on the line to stop Garrett and the forces of Hydra. But when the dust settles, Coulson will find…

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns…

Sheldon and the gang are confused when a young grad student is attracted to him.

Sam has a vision of Dean shooting a defenseless man, and they go to the town of River Grove, where they find the townspeople have been possessed by a virus…

Rick and the group leave Atlanta and encounter a threat on the highway the likes of which they’ve never seen. Elsewhere, the group search for a missing person.

Dorie Russell is waiting for quintuplets, all 5 girls. Her husband seems more concerned than she is but she is set to bring her babies to their term of 36…

Leonard and his friends stage an intervention to force Sheldon to face his fear of driving.

Dean calls a demon to make a deal to save a man named Evan Hudson, in exchange for himself. While making the deal, the demon confronts Dean’s worst nightmare about…

Julia and Kady enlist Quentin, Margo, Eliot, and Penny for a magical heist.

Ward’s betrayal and Hydra’s shocking secrets are revealed as Coulson’s team goes undercover on a mission that leaves no one unscathed.

It’s Thanksgiving at Seattle Grace Hospital but the holiday’s festivites are less than in order. Meredith and Derek try to counsel a family after their relative has had a seriously…

Raj gets an inflated ego and makes a play for Penny after being referenced in a magazine article.

Sam and Dean investigate the murder of a lawyer and his wife, who claimed to have seen a ghost before they were killed. However, local authorities arrest the Winchesters after…

Harvey meets his match in a cocky opposing counsel in a class action lawsuit, and Mike unknowingly helps frame Rachel as a traitor to the firm.

Peña and Carillo close in on Gacha, while Murphy tries to protect pro-extradition candidate Gaviria from a notorious assassin connected to Pablo.

Meredith tries to avoid the Shepherds. Cristina and Burke go out on a date and end up getting caught up in their jobs. Derek asks Meredith not to ignore him…

Sheldon creates a monster when he introduces Penny to online gaming.

Sam and Dean investigate the slayings of blonde women and find that the ghost of the first known serial killer in US history is responsible. Jo disobeys Ellen’s wishes and…

With no one left to trust, Agent Maria Hill (Cobie Smulders) teams up with Coulson while S.H.I.E.L.D. is being destroyed.

Cristina, Izzie and Meredith take care of Shane, a man who appears to be crazy and claims that he is pregnant. Shane’s case induces a spreading fascination among the staff….

A jealous Leonard reacts to Penny’s new guy by rebounding with Leslie.

Sam and Dean meet Andy Gallagher, a slacker with psychic powers of persuasion. Once the brothers learn that Andy’s family was visited by the Demon, Sam wonders if he could…

Hoping to get under Renata’s skin, Madeline organizes a trip to compete with Amabella’s birthday party. After another argument, Celeste succumbs to Perry’s charms before their first session with a…

Train Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really weird cases. Except Addison and Izzie. They work with a woman who is…

Penny’s first date with Leonard goes awry; Penny finds Sheldon to be an unwilling confidant.

Dean and Sam investigate the death of a young college student who died in a car accident, but whose grave is now surrounded by a circle of dead plants.

With their WORLD turned upside down, Coulson races to save the life of his one true love as the mystery of “The Cellist,” which began in Marvel’s The Avengers, is…

While Madison struggles to keep Nick from crippling withdrawal, Travis ventures out to find his son before the city of Los Angeles falls.

Cristina goes right back to working right after being discharged. Izzie isn’t talking to Alex. Derek and Meredith treat a patient. George and Alex get stuck in an elevator.

Sam and Dean encounter a vampire hunter whose obsession may get them all killed.

After the events at the hospital, the brothers have no idea where the demon that killed their mother is hiding. While biding their time trying to come up with an…

With Colonel Glenn Talbot now on their trail, Coulson and his team seek refuge in the last place anyone would look, where they begin to uncover S.H.I.E.L.D.’s most dangerous secrets–secrets…

Klaus just isn’t himself after seeing Dr. Orwell, an optometrist with oddly optimistic patients. Meanwhile, Violet works to clear her parents’ names.

As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn’t improve her demeanor any. And Meredith’s mother, Dr. Ellis Grey,…

In the aftermath of the car crash, the surviving Winchesters go to the hospital, where one is stalked by a Reaper while another must consider sacrificing himself to save the…

Eliot attempts to summon Alice’s spirit while Julia and Kady follow leads to rid them of Reynard and his unborn child. In Fillory, Eliot and Margo find that they have…

Cristina and Meredith try to figure out if Cristina should tell Burke that she’s pregnant right before Cristina faces an emergency. Alex and Izzie get closer while Meredith’s mother gets…

Mike is tasked with reigning in a modern day Robin Hood whose illicit deeds are putting a client’s business at risk. Also, Louis must resolve his differences with Harvey to…

Coulson and his team find themselves without anyone they can trust, only to discover that they are trapped with a traitor in their midst.