Sam and Dean look to occult lore for a solution to their latest problem, but instead of a resolution, they find much more than either of them had anticipated.

To save one of their own, Rick’s group must venture outside the walls; their experience changes their lives forever.

Sam and Dean search for a Crocotta that uses the phone and computer as a means to communicate with people. Its goal is to get people to commit suicide and…

This episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member’s condition. Callie and George have a talk about…

Denny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of a friend in his hands as he operates on…

George and Derek work together, Denny still doesn’t have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to…

The staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that involved a married couple, their…

Addison’s patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient’s husband won’t use contraceptives. Derek treats a divorce attorney who asks if Derek…

After the fight between Jake and Sam, Dean has to make the ultimate sacrifice for his brother. Meanwhile the Yellow-Eyed Demon has his new servant and plans to unleash the…

Meredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious head injury. Bailey gets in on Andrew’s surgery because she’s worried that her…

After a series of deaths at the hospital some of the staff become very superstitious. Izzie worries about Denny and gets confronted by Alex. A patient with OCD drives Cristina…

The doctors are up to their necks in their usual levels of drama. Meredith is dealing with the backlash of sleeping with George, George and Burke are bonding in ways…

Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what’s up. Derek and Addison are experiencing their own…

Cristina is bothered by a new year’s mandatory work limit. Izzie patient, Denny Duquette, wants two things: 1. a heart transplant, 2. Izzie. Addison detests Derek’s trailer, Derek visits Meredith’s…

In the aftermath of the car crash, the surviving Winchesters go to the hospital, where one is stalked by a Reaper while another must consider sacrificing himself to save the…

When Meg boasts that John is her prisoner, the boys visit a friend of their father’s to get information about demonic possessions and ways to trap a demon. It turns…

John has realized where the demon will strike next and the Winchesters head there to stop the next killing. But Meg begins killing John’s friends and demands the Colt or…

To obtain a mystic gun capable of destroying the demon that killed their mother, Sam and Dean must team up with their father John and face off against vampires.

Sam and Dean battle a Shtriga, a witch that sneaks into childrens’ bedrooms and sucks the lives out of them. Dean must relive his childhood when he remembers that he…

Sam has a reunion with a girl he once met, Meg, but it turns out that she is using the brothers to lure their father John to his doom.

Sam and Dean finally make contact with their father, but he tells them to stop looking for him and sends them on another ghost-hunting job. Frustrated with their father’s evasiveness,…

Sam is haunted by a vision of a woman trapped in his childhood house and convinces a reluctant Dean that they need to go home. Upon arrival, they meet the…

Two brothers, Sam and Dean Winchester, witness their mother’s paranormal death as children and grow up trained to fight by a distraught father who wants nothing more then to hunt…